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Minimally Invasive Lumbar Spine Surgery has brought a drastic change in the way patients experience relief from back pain. It is no longer a general procedure, but it is designed specifically for each patient, guided by his or her unique anatomy, pathology, and lifestyle. This demands extensive preoperative evaluation, including advanced imaging techniques such as MRI and CT scans, to determine precisely where the pain is coming from and to plan for the surgical approach. Further anatomical and functional characteristics of the individual, such as bone density, muscle mass, and overall health, are also considered in tailoring theMinimally Invasive Lumbar Spine Surgeryto achieve optimal surgical outcomes with minimum morbidity.